|aarongarc||Дата: Вторник, 06.10.2015, 16:25 | Сообщение # 1|
Rare fatalities associated with albendazole use have been reported due to granulocytopenia or pancytopenia. Bone marrow suppression, aplastic anemia, and agranulocytosis in patients with and without underlying hepatic dysfunction have been observed with albendazole.
If hepatic enzymes exceed twice the upper limit of normal, discontinuation of albendazole treatment should be considered based on individual patient circumstances.
Patients being treated for neurocysticercosis should receive anticonvulsant and steroid therapy as required. http://nickolasall26.tumblr.com/post/130542620551/generic-name-albendazole-verbal - Albendazole Deutschland (oral or IV) should be considered to prevent cerebral hypertensive episodes during the first week of treatment.
Preexisting neurocysticercosis may be found in patients treated with albendazole for other conditions. If patients experience neurological symptoms soon after treatment due to an inflammatory reaction caused by parasitic death within the brain, appropriate steroid and anticonvulsant therapy should be started at once.
Cysticercosis may involve the retina in rare cases. Before starting neurocysticercosis therapy, the patient should be examined for retinal lesions. If such lesions are present, the need for anticysticeral therapy should be weighed against the possibility of retinal damage caused by albendazole-induced changes to the retinal lesion.
If pregnancy occurs while taking albendazole, therapy should be discontinued at once and the patient should be apprised of the potential risk to the fetus.
Data not available
Administration of albendazole with a fatty meal (fat content 43.1 g) has shown an increase in plasma concentrations of albendazole sulfoxide in a dose-proportional manner over the therapeutic dose range.
In patients who have difficulty swallowing the tablets whole, the tablets should be crushed or chewed and swallowed with a little water.